IL6 and rheumatoid arthritis: Laser acupuncture could reduce HAQ (MD = −0.15, 95% CI: −0.28 to −0.01, P=0.034), the RA quality of life questionnaire (RAQoL, MD = −2.32, 95% CI: −4.40 to −0.25, P=0.028), CRP (MD = −35.24, 95% CI: −36.49 to −33.99, P < 0.001), and interleukin-6 (IL-6, MD = −29.63, 95% CI: −49.34 to −9.92, P=0.003), while compared to control group.