The main compounds of SQYG included gamma-sitosterol, β-sitosterol, suffruticoside A, choline, cetylic acid, stigmasterol, hexadecanoicacid, 3-hydroxycoumarin, baicalin, ginsenoside Rb1, ginsenoside Rg1, ginsenoside Re, danshenol A, salvianolic acid B, danshenol B, astragaloside IV, 3 beta-hydroxytanshinone IIA, and isoastragaloside I. The PPI network results indicated that INS, ALB, IL6, TNF, TP53, IL1B, VEGFA, APOE, CTNNB1, and PPARG were key targets of SQYG on AD. This evidence concerns the gene TP53 and Alzheimer disease.