Most prominently, all dura clusters were enriched for genes associated with “response to sterol” and “myeloid leukocyte migration,” with some clusters enriched in genes associated with “inflammatory response” and “negative regulation of DC differentiation.” Meanwhile, all tumor clusters were enriched for genes associated with “defense response,” “cellular response to IFNγ,” and “response to unfolded protein.” In particular, MHC class II genes such as HLA-DRA and HLA-DRB1 were also upregulated by tumor-specific clusters. Here, HLA-DRB1 is linked to neoplasm.