First, we identified neighboring genes interacting with RUNX1 using the STRING website; the detailed results are shown in Fig. 10A. To better analyze the functional mechanism between RUNX1 expression and human cancers, we retrieved the Metascape database to construct a PPI enrichment analysis and obtained two of the most significant MCODE components from the analysis results (Fig. 10B). This evidence concerns the gene RUNX1 and cancer.