According to most algorithms, the infiltration level of CD8 + T cell was significantly negatively or positively associated with RUNX1 expression in all three tested tumors, including BRCA-Her2 (Rho = -0.379, P = 1.03e-03), lymphoid neoplasm diffuse large B-cell lymphoma (DLBC) (Rho = 0.532, P = 3.46e-4), and UVM (Rho = 0.665, P = 1.04e-10) (Fig. S3A-B). Here, RUNX1 is linked to lymphoid neoplasm.