Of note, expression of the lactate and butyrate transporter solute carrier family 16 member 1 (SLC16A1/ MCT1) is reduced in ulcerative colitis, along with genes encoding enzymes of the mitochondrial β-oxidation pathway96, indicating that reduced availability of substrates might arise from bacterial alterations as well as cellular disturbances. Here, SLC16A1 is linked to ulcerative colitis.