AKT1 and cancer: Upon identification of key differentially expressed genes between drug-sensitive and -resistant cancer, the GO terms for biological processes significantly enriched from this set of DEGs for most of the drug cases were: signal transduction, cell adhesion, apoptotic process, proteolysis, and cell cycle, and KEGG pathways gene set were enriched in proteoglycans pathway in cancer, focal adhesion pathway, metabolic pathway and PI3K/Akt signaling pathway.