GFAP and stroke disorder: PT stroke causes an increase in astrocyte (GFAP) expression within the peri-infarct region of the brain compared to sham (C57Bl/6: sham: 1.56% ± 0.87%, 18 min: 15.47% ± 2.78%; FVB/N sham: 0.94% ± 0.46%, 18 min: 17.896% ± 2.95%, P < 0.001, Fig. 3B).