XRCC4 and glioblastoma: LncSBF2-AS1 was found to be highly expressed in TMZ-resistant GBM cells and tissues, targeting lncSBF2-AS1–sensitized resistant GBM cells to TMZ resistance through serving as ceRNA for sponging miR-151a-3p, resulting in the suppression of its endogenous target, X-ray repair cross-complementing 4 (XRCC4), which increases DNA double-strand break repairability in GBM cells (Zhang et al., 2019).