In view of the great importance of circRNAs in HCC, we previously revealed that circ_0011385 enhances HCC cell proliferation and tumor activity via regulation through the miR-361-3p/STC2 axis and that circCRIM1 facilitates HCC progression and angiogenesis by sponging miR-378a-3p (9, 11). The gene discussed is STC2; the disease is neoplasm.