Moreover, some large cohort studies found statistically significant differences in mutation status between right-sided and left-sided CRC for several genes, including KRAS, BRAF, and FBXW7, as well as for several pathways, including RAS/MAPK, TGF-β, and p53 signaling pathways (5, 7). The gene discussed is KRAS; the disease is colorectal carcinoma.