In PC-9 CSCs, overexpression of p53 significantly inhibited malignancies in PC-9 CSCs, which were reversed by the addition of PFT-α, indicating that p53 may, at least, partially regulates malignancies via ALKBH5 in NSCLC CSCs (Figures 7A–D). Here, TP53 is linked to non-small cell lung carcinoma.