In particular, we focused our attention on the proto-oncogenic transcription factor c-MYC, which is overexpressed in TNBC compared to other BC subtypes (Supplementary Figure 1B) (46) and was shown to drive transcription of both NEK2 (32) and its putative cofactors PTBP1 (12) and KHDRBS1 (13) in other tumoral context. Here, PTBP1 is linked to breast cancer.