XPC and non-small cell lung carcinoma: While studies have suggested decreased XPC expression in NSCLC tumor cells compared to surrounding lung (119), in 21 patients with NSCLC in which blood, tumor and lung tissue were collected, XPC mRNA expression was found to strongly correlate between blood and NSCLC tumor tissue, supporting the potential use of a minimally invasive blood draw as a prognostic and therapeutic biomarker (143).