In addition, the co-administration of GE and MA in H292/GR cells also induced a potent decrease of phosphorylated modification of EGFR signaling pathways molecules, which further indicated that the EGFR signaling is related to the synergistic effects of GE and MA on drug-resistant NSCLC cells (Figure 3). This evidence concerns the gene EGFR and non-small cell lung carcinoma.