When damage occurs in hepatocytes, it stimulates the production of large amounts of ROS in the liver, and the accumulation of excessive ROS can exceed the normal range of the antioxidant system in the body, allowing the occurrence of oxidative stress that causes abnormal fibrosis in the liver, while the activation of mTOR accelerates liver fibrosis when the organism is in a state of nutritional deficiency [95]. This evidence concerns the gene MTOR and Hepatic fibrosis.