Studies have shown that ursolic acid (UA) can regulate EMT or MFB via Rho [136, 137], improve the integrity of the intestinal barrier, reduce intestinal flora disorders [138, 139], and modulate the NOX4/NLRP3 inflammatory vesicle signaling pathway to attenuate liver fibrosis [140]. This evidence concerns the gene NLRP3 and Hepatic fibrosis.