Furthermore, studies on pharmacologic mechanisms have reported that GZFL can induce serious apoptosis and deter the proliferation and metastasis of endometrial cells in a rat with endometriosis by reversing suppression of survivin and the B-cell lymphoma (Bcl)-2/BCL2-associated X protein (Bax) ratio, which is related to the mitochondrial apoptotic pathway. This evidence concerns the gene BAX and endometriosis.