CCL3 and necrotizing enterocolitis: Similarly, CCL3 levels in the intestinal tissues of NEC model mice were significantly higher than those of control mice (Figure 1B), which was further verified by immunofluorescence (IF) and immunohistochemistry (IHC) staining, revealing that CCL3 expression in the intestinal tract of NEC mice was significantly higher than that in the control group, predominantly in the epithelium and lamina propria of the intestinal mucosa (Figures 1C, D).