However, regardless of impaired neutrophil recruitment in VEC-Y731F mice, the degree of resulting kidney injury in WT and VEC-Y731F recipient mice infused with plasma from CLP mice was similar according to plasma creatinine (Figure 5C) and the urinary AKI biomarkers NGAL, KIM-1, TIMP2 and IGFBP7 (Figures 5D–G). This evidence concerns the gene IGFBP7 and acute kidney injury.