Other series have focused on an AFP limit of <400 ng/ml and found a low 5-year recurrence rate of 4.9% in patients with a total tumor diameter of <8 cm (37), or a 4-year recurrence rate of 9.4% in patients with a total tumor volume (TTV) of <115 cm3 and AFP <400 ng/ml (38). The gene discussed is AFP; the disease is neoplasm.