Whereas in patients with an AFP level ≤20 ng/ml, an up to 12 sum of HCC number and diameter was acceptable, which decreased with increasing AFP to 10 (AFP 21–200 ng/ml), 7 (AFP 201–500 ng/ml), and 5 (AFP 501–1,000 ng/ml) (Figure 6). This evidence concerns the gene AFP and hepatocellular carcinoma.