AFP and hepatocellular carcinoma: The additional value of the AFP level to improve patient selection in this context was first shown in the French AFP model, in which the upper limit of size and number could be increased from the MC criteria to ≤6 cm in cases of ≤3 nodules and to ≤3 cm in cases of ≥4 tumor nodules in patients with pre-LT AFP levels ≤100 ng/ml without a significantly increased risk of HCC recurrence (33).