The aGAPSS is a useful tool to predict thrombosis in the general population of APS patients (Ruiz-Irastorza et al., 2011; Chighizola et al., 2018; Garcia and Erkan, 2018), alike is the presence of multiple aPL (i.e., triple positivity) (Pengo et al., 2010; Udry et al., 2019). Here, FASLG is linked to autoimmune polyendocrinopathy.