P2RY14 and diabetic kidney disease: It was also a surprising phenomenon that the level of ROS (a general indicator of ferroptosis) in the DM + P2Y14 shRNA group and DM + naringin group was even lower than that in the control group, which was also similarly demonstrated in another paper entitled “Inhibition of ferroptosis by upregulating NRF2 delayed the progression of diabetic nephropathy” (Li et al., 2021).