PPIG and metabolic dysfunction-associated steatotic liver disease: Moreover, NAFLD is poised to have an appreciable impact on the expression and function of ATP-binding cassette efflux transport proteins (e.g., MRPs), uptake transporters (e.g., OATPs), and metabolic enzymes such as CYP, UDP-glucuronosyltransferases (UGT) and sulfotransferases (SULT) (99–101).