Moreover, PCA,2-(3-methoxy-4-hydroxy-phenyl)-6-(3-hydroxypropyl)-5-methoxybenzo[b]furan (an active compound identified from Danshen) and Danshensu Bingpian Zhi are efficient natural PPARγ agonists that exhibited excellent effects on insulin resistance, antiadipogenic, hepatic steatosis and inflammation (197, 198). The gene discussed is PPARG; the disease is fatty liver disease.