PPARG and Insulin resistance: Moreover, PCA,2-(3-methoxy-4-hydroxy-phenyl)-6-(3-hydroxypropyl)-5-methoxybenzo[b]furan (an active compound identified from Danshen) and Danshensu Bingpian Zhi are efficient natural PPARγ agonists that exhibited excellent effects on insulin resistance, antiadipogenic, hepatic steatosis and inflammation (197, 198).