The enrichment analysis of 137 ferroptosis-related differential genes shows that KEGG is mainly enriched in autophagy-animals, ferroptosis, HIF-1 signaling pathway, FoxO signaling pathway, VEGF signaling pathway, PD-L1 expression and PD-1 inspection point pathway in cancer, MAPK signaling pathway, PI3K-Akt signaling pathway, and JAK-STAT signaling pathway. The gene discussed is PIK3CA; the disease is cancer.