The HR values of APOD, GABARAPL2, CD59, ANGPT1, TAP1, CALD1, COL24A1, MS4A4A, CD93, PECAM1, SPRED1, SLC77A14, BNC2, PRPH2, SMAD5, NR4A3, COL6A3, and AMOTL1 were more than 1, denoting poor prognosis of gastric cancer. The gene discussed is SPRED1; the disease is gastric cancer.