GSK3B and myocardial infarction: TTC and HE staining noted that compared with the GSK3β WT mice, GSK3β CKO mice showed a reduced myocardial infarction area, alleviated pathological changes in myocardial tissues, and decreased infiltration of necrotic cardiomyocytes and centrifugal cells (Figures 2(c) and 2(d), Supplementary Figure 1B).