Expression levels of IL2RB were remarkably associated with all six tumor invading lymphocytes including B cells (R = 0.463, 0.585, and 0.684, P < 0.001), CD4 + T cells (R = 0.323, P = .0039; R = 0.695, P < 0.001; and R = 0.675, P < 0.001), CD8 + T cells (R = 0.819, 0.665, and 0.766, P < 0.001), dendritic (R = 0.614, 0.774, and 0.818, P < 0.001), macrophage (R = 0.549, 0.293, and 0.759, P < 0.001), and neutrophil (R = 0.669, 0.742, and 0.496, P < 0.001) in ACC, BRCA, and CHOL cancers. Here, IL2RB is linked to neoplasm.