Imatinib prevention by oral gavage (250 mg/kg) significantly (p ≤ 0.05) decreased VEGFaa, VEGFab, IL-6, CCL2 and BDNF LP mRNA but did not affect NGF LP mRNA in mice with 4 h CYP-induced cystitis (1.6–6.5-fold) (Figures 2A–F). Here, PPIG is linked to chronic cystitis.