The selected miRNA candidates were tested in plasma by RT-qPCR in two patient groups: 1) in five ACTH secreting PitNET patients with plasma samples taken before and 24 hours after surgery, 2) in 12 ACTH secreting PitNET patients vs. 9 non-functioning PitNET patients.<h4>Results</h4>BIPSS concluded that the highest amount of ACTH was released in the sinistral side at the 5<sup>th</sup> minute mark indicating a presence of a tumor. Here, POMC is linked to neoplasm.