APOB and myocardial ischemia: A suggestive causal effect was also observed for IHD (OR =1.277, 95% CI: 1.075-1.516, p = 0.005) and MI (OR =1.220, 95% CI: 1.002-1.484, p = 0.047), and increased level of apoB (OR =1.056, 95% CI: 1.011-1.104, p = 0.015) (Figure 6).