Inhibition of the common shedding proteases BACE1 and BACE2, which are expressed in A549 cells (Zecha et al, 2020), with the drug C3 (Stachel et al, 2004) did not alter GFP expression, ruling out an involvement of both proteases in SARS‐CoV‐2 spread in this infection model (Fig 1D). Here, BACE1 is linked to infection.