CD36 is a scavenger receptor [75] and has been linked to the pathogenesis of atherosclerosis and Alzheimer’s disease through its recognition of modified endogenous ligands, including oxidized low-density lipoprotein (oxLDL) [76], fibrillar amyloid-β [77], and soluble amyloid-β [78]. Here, CD36 is linked to early-onset autosomal dominant Alzheimer disease.