APOE and Alzheimer disease: The influence of APOE status on A\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\upbeta$$\end{document}β- and p-tau-associated microgliosis has been observed in animal models, morphologic human brain studies, and by single-nucleus RNA-sequencing (snRNA-seq) analysis of microglial populations in AD human frontal cortex [3, 5, 31–33, 52, 53].