KLF12 and neoplasm: To further validate that KLF12 is participated in the pro-tumour effects of LncRNA-PACERR in TAMs, we got similar results to LncRNA-PACERR by using qPCR, flow cytometry, CCK8, colony formation and Transwell assays, and found that overexpression of KLF12 can promote the expression of LncRNA-PACERR (Fig. 5m, Additional file 6: Fig. S7f, g and Fig S8a-e).