LAMA4 and cardiovascular disorder: In contrast, the pathogenic risk of LAMA4 p.A225P (rs ID: rs782121531, gnomAD: 0.00006) is classified as “LB” and “B” by the Clinvar database and ACMG guidelines but lacked genetic verification in familial/sporadic cases of cardiovascular diseases (https://www.ncbi.nlm.nih.gov/clinvar/variation/VCV000213580.6).