The work presented in this report was initiated following the discovery of a missense mutation in the PH domain of the AKT3 gene in a patient with schizophrenia in an exome sequencing study organized by the Stanley Center for Psychiatric Research at the Broad Institute (https://schema.broadinstitute.org/gene/ENSG00000117020) [30]. Here, AKT3 is linked to schizophrenia.