CD74 and neoplasm: To further verify the above results, we tested MHC-II, APOE, CD74, APP, and Aβ in ACP tumor tissues and found MHC-II, APOE, and CD74 expression on microglia (IBA1+) in the ACP nerve junction area (Fig. 6C–E), suggesting that these microglia are also in the same state of inflammatory activation.