APOB and inherited lipid metabolism disorder: This is consistent with the 2019 ESC Guidelines on Dyslipidaemias, which highlight that apoB provides an accurate estimate of the total concentration of atherogenic particles under all circumstances Of note, considering the potential inaccuracy of LDL-C in dyslipidaemia among patients with DM, guidelines highlight that apoB is superior to low density lipoprotein cholesterol (LDL-C) in estimating the atherosclerotic cardiovascular risk in this population and therefore should be the preferred measurement [34].