CSF3 and infection: Detailed information on the clinical features of the neutropenia, recurrent infections, extra-hematopoietic features, G-CSF doses, G-CSF response, PBSCT, Ig levels, BM histology of maturation arrest, myelokathexis, MPO-positive cell percentage and MPO grade, and variants detected by WES or TS in each patient is described in Table 1 and Supplementary Table S1.