We next addressed if the trans-interaction between SLAMF7 on macrophages and neuroblastoma cells could occur by examining SLAMF7 expression on the tumor cells relative to those of B4GALNT1 (GD2 synthase gene) and ST8SIA1 (GD3 synthase gene) in high-risk neuroblastoma tissues. This evidence concerns the gene ST8SIA1 and neoplasm.