L1CAM and non-small cell lung carcinoma: In the past few years, a host of research have been carried out around the world to discuss the expression and function of L1CAM in human malignancies of different patient samples.5, 6, 7, 8, 9, 10, 11, 12, 13 It has been demonstrated as a predictive factor of poor prognosis in Non-Small Cell Lung Cancer (NSCLC), cervical cancer, endometrial cancer, gastric cancer, glioma, renal cell cancer, ovarian carcinoma, melanoma, colon cancer, and pancreatic cancer.