XIAP and brain ischemia: This protective effect, including the restoration of motor function and coordination, was maintained during the 28 days of observation of the animals, which is consistent with a decrease in the expression of B-cell lymphoma 2 (Bcl-2) and X-linked inhibitor of apoptosis protein (XIAP) (The Bcl-2 family and XIAP are known to play an important role in the evolution of injury following cerebral ischemia) [83].