Excessive levels of ROS can be controlled in both the tumor and physiological environment using antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), and peroxiredoxins (Prxs), as well as nonenzymatic antioxidants, such as vitamins E and A [3, 4]. Here, SOD1 is linked to neoplasm.