Wu et al. found that solasonine enhanced the sensitivity of oesophageal cancer EC9706 and KYSE30 cells to 5‐flurouracil (5‐FU) and cisplatin through inducing miR‐138 expression,20 and Hasanain and colleagues reported that solasonine induced autophagy to exert anti‐proliferative activity non‐small‐cell lung cancer A549 cells, human breast cancer MCF‐7 cells and human prostate cancer DU145 cells by triggering endoplasmic reticulum stress and inhibiting Akt/mTOR signalling.21 This evidence concerns the gene MTOR and Familial prostate cancer.