These results suggest that Mcl-1 is affected and regulated by a variety of protein kinases, transcription factors, miRNA, etc. The molecular interactions and associations of Mcl-1 in oral cancers are summarized in Table 3, whereas and the protein–protein interactions (PPIs) between the identified biomarkers are presented in Fig. 3. The gene discussed is MCL1; the disease is lip and oral cavity carcinoma.