Furthermore, Tspan7 has been identified as a promising biomarker and functional regulatory protein associated with several cancers such as multiple myeloma [26], clear-cell renal cell carcinoma [27], head and neck squamous cell carcinoma [28], primary uterine leiomyosarcoma [29], and desmoplastic small round-cell tumors [30]. This evidence concerns the gene TSPAN7 and AL amyloidosis.