DM-specific autoantibodies were present in 61.3% of DM patients, with anti-MDA5 (70 [20.9%]), anti-TIF1-γ (57 [17.1%]), anti-Mi-2(26 [7.8%]), anti-NXP2(40[12.0%]), and anti-SAE (7 [2.1%]). This evidence concerns the gene IFIH1 and dermatomyositis.