The sensitivity of the uDNA methylation test for BC is 82.9%, generally lower than reported values for multigene panels (92% for GHSR/MAL, 90.0% for OTX1/SOX1-OT, 90.5% for VIM/OSTM1/SLC4A10/AC092805.1/ONECUT2, 88.1–91.2% for ONECUT2/VIM and 62.5–90.0% for EpiCheck). Here, OTX1 is linked to breast cancer.