Hua Hua C C Barnetche Barnetche T T Combe Combe B B Effect of methotrexate, anti-tumor necrosis factor α, and rituximab on the immune response to influenza and pneumococcal vaccines in patients with rheumatoid arthritis: a systematic review and meta-analysis Effect of methotrexate, anti-tumor necrosis factor α, and rituximab on the immune response to influenza and pneumococcal vaccines in patients with rheumatoid arthritis: a systematic review and meta-analysis Arthritis Care Res Arthritis Care Res 2014 2014 66 66 7 7 1016 1016 1026 1026 10.1002/acr.22246 10.1002/acr.22246. The gene discussed is TNF; the disease is influenza.