To confirm the biological relevance of BCL9L, SOX4 and AKT1 in mediating NAT10 function in BLCA, we performed rescue experiments using pCDNA 3.1 (+)‐BCL9L, pCDNA 3.1 (+)‐SOX4 or pCDNA 3.1 (+)‐AKT1 recombinant plasmids (Figure 5A and B). This evidence concerns the gene AKT1 and bladder transitional cell carcinoma.