However, the morphology of HMC3 (Fig 2C) or U251 (Fig 2D) cells expressing NS1, NS2B, NS3, or NS4B was similar to the control cells after infection, and the cells were shrunk and suspended; the morphology of the infected cells expressing NS2A or NS4A remained as healthy as the control cells without infection. The gene discussed is KRAS; the disease is infection.